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Highlighting the efforts of Abu Dhabi Stem Cells Middle (ADSCC) to pioneering analysis and remodeling healthcare, a milestone has been achieved in one in every of its ongoing scientific trials, the Extracorporeal Photopheresis (ECP) for Optimum Administration of A number of Sclerosis (PHOMS) examine.
The examine at ADSCC, a PureHealth subsidiary, the most important healthcare platform within the Center East, evaluates the security and efficacy of utilizing ECP to deal with folks with a number of sclerosis (MS). As an immunomodulatory remedy used for some most cancers therapies, graft-versus-host illness (GvHD), and autoimmune ailments, ECP on this examine seeks to alleviate MS signs by rebalancing the immune system of the affected person.
ADSCC has revealed that one of the success tales throughout the PHOMS trial entails a UAE resident, recognized with MS since 2019, who previous to taking part within the examine skilled debilitating signs equivalent to problem strolling, imbalance, gait disturbance, slurred speech and cognitive impairment. After six months of remedy with ECP, the affected person has reported vital enhancements in mobility, lowered imbalance-related points and clearer speech. These enhancements have been persistently noticed throughout his three-month neurological testing.
In 2022, ADSCC’s trial has obtained approval from the Division of Well being – Abu Dhabi (DOH), and since then has enrolled a gaggle of contributors recognized with Secondary Progressive A number of Sclerosis (SPMS) or Relapsing-Remitting A number of Sclerosis (RRMS). The trial can also be registered within the international scientific trials registry ClinicalTrials.gov.
Dr. Yendry Ventura, Principal Investigator within the PHOMS examine at Abu Dhabi Stem Cells Middle, stated: “Scientific trials and analysis play a pivotal function in advancing healthcare and bringing cutting-edge improvements throughout the public’s attain. These endeavours drive scientific progress, improve affected person care and bridge the hole between groundbreaking discoveries and real-world healthcare options. In keeping with the imaginative and prescient of the UAE’s management and as leaders in scientific analysis in UAE, our scientific trials and analysis efforts at ADSCC signify a unprecedented chapter in our medical historical past and expedite our pursuit of a more healthy society and establishing Abu Dhabi as a distinguished international vacation spot for healthcare, innovation and analysis. The scientific consequence of our sufferers on this scientific trial is a milestone that underscores our dedication to rewriting the narrative of MS remedy within the area.”
Dr. Fatima Al Kaabi, Government Director of the Abu Dhabi Bone Marrow Transplant Program (AD-BMT) at Abu DhabI Stem Cells Middle, Investigator in PHOMS Research, and Vice Chair of the Nationwide MS Society, stated: “ADSCC is proud to be on the forefront of progressive analysis within the area of a number of sclerosis remedy, and thru groundbreaking therapies and analysis, our goal is to enhance MS sufferers’ high quality of life. Unveiling the impression of ECP in folks with MS is a journey that began a yr in the past by means of the PHOMS scientific trial at ADSCC throughout which our world-class physicians, scientists and devoted researchers labored collectively to pioneer cutting-edge therapies for MS sufferers. Within the pursuit of excellence, we recognise that each discovery we make has the potential to alter lives immediately and tomorrow.”
Dr. Yandy Marx Castillo Aleman, Head of Scientific Trials and Sub-Investigator in PHOMS examine at Abu Dhabi Stem Cells Middle, stated: “PHOMS trial has already made vital strides with our contributors. Sufferers are accepted following particular scientific, laboratory and imaging standards. Throughout the framework of the PHOMS examine, sufferers bear a sequence of 28 ECP procedures spanning six months, adopted by a further interval of six months for monitoring by the ADSCC Neurology staff. The promising outcomes we noticed with our sufferers permit us to maneuver ahead with the PHOMS examine which will likely be accomplished in one other 12 months.”
Dr. Ruqia Mir, Neurology Advisor and Sub-Investigator in PHOMS examine at Abu Dhabi Stem Cells Middle, stated: “This progressive process utilized in our examine, ECP, entails the remedy of a affected person’s autologous leukocytes with a photoactivatable drug, adopted by publicity to UVA gentle and subsequent reinfusion into the affected person. ECP has proven promising leads to addressing a variety of medical circumstances, and now with our scientific trial, is providing hope to people residing with MS. By the PHOMS examine and our dedication to transformative analysis, we try to offer further remedy choices for sufferers dealing with this difficult situation.”
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